Zibotentan

  • Zibotentan
Catalog No.: 3176

Zibotentan (ZD4054) is a specific Endothelin (ET)Aantagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.

Chemical Name:
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid
 

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Biological Activity:
Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
Technical Data:
M.W. 424.43
Formula: C19H16N6O4S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 186497-07-4
References:
Morris CD, et al. Br J Cancer, 2005, 92(12), 2148-2152. Rosanò L, et al. Exp Biol Med (Maywood), 2006, 231(6), 1132-113 Rosanò L, et al. Cancer Res, 2007, 67(13), 6351-635 Rosanò L, et al. Mol Cancer Ther, 2007, 6(7), 2003-201

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Tags: Dyes & Statins, Endoplasmic Reticulum Staining, Zibotentan, 186497-07-4

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