Paclitaxel

  • Paclitaxel
Catalog No.: 3320

Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

Chemical Name Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

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Biological Activity:
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Technical Data:
M.W. 853.91
Formula:

C47H51NO14

Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 33069-62-4
References:
Wang J, et al. Anticancer Drugs. 2003, 14(1), 13-19. Sun RG, et al. Gen Physiol Biophys. 2012, 31(1), 1-10. Zhang XH, et al. Cancer Lett. 2012, 322(2), 213-222. Chang J, et al. Breast Cancer Res Treat. 2012.

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Tags: Inhibitors, Cytoskeletal Signaling, Microtubule Associated, Paclitaxel, 33069-62-4

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