Vincristine

  • Vincristine
Catalog No.: 3189

Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.

Chemical Name:
1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone
 

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Biological Activity:
Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.
Technical Data:
M.W. 923.04
Formula: C46H58N4O14S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 2068-78-2
References:
Jordan MA, et al. Cancer Res, 1985, 45(6), 2741-2747. Gidding CE. Crit Rev Oncol Hematol, 1999, 29(3), 267-287. Tu Y, et al. Int J Mol Med, 2013, 31(1), 113-119. Donoso JA, et al. Cancer Res, 1977, 37(5), 1401-1407. Horton JK, et al. Biochem Pharmacol, 1988, 37(20), 3995-4000. Baguley BC, et al. Eur J Cancer, 1991, 27(4), 482-487.

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Tags: Inhibitors, Cytoskeletal Signaling, Microtubule Associated, Vincristine, 2068-78-2

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