Dynasore

  • Dynasore
Catalog No.: 3125

Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase.

Chemical Name:

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide

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Biological Activity:
Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase.
Technical Data:
M.W. 322.31
Formula: C18H14N2O4
Solubility: DMSO
Purity: 98%
Storage:
CAS No: 304448-55-3
References:
Macia E, et al. Dev Cell, 2006, 10(6), 839-850. Newton AJ, et al. Proc Natl Acad Sci USA, 2006, 103(47), 17955-17960. Abban CY, et al. Am J Ther, 2008, 15(4), 304-311.

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Tags: Inhibitors, Cytoskeletal Signaling, Dynamin, Dynasore, 304448-55-3

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