AUY922 (NVP-AUY922)

  • AUY922 (NVP-AUY922)
Catalog No.: 3040

AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.

Chemical Name5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide

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Biological Activity:
AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.
Technical Data:
M.W. 465.54
Formula: C26H31N3O5
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 747412-49-3

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Tags: Inhibitors, Metabolism, HSP (e.g. HSP90), AUY922 (NVP-AUY922), 747412-49-3

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