AT7867

  • AT7867
Catalog No.: 3035

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.

Chemical Name: 4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine

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Biological Activity:
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.
Technical Data:
M.W. 337.85
Formula: C20H20ClN3
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 857531-00-1
References:
Grimshaw KM, Mol Cancer Ther, 2010, 9(5), 1100-1110.

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Tags: Inhibitors, PI3K/Akt/mTOR, S6 Kinase, AT7867, 857531-00-1

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