A-769662

  • A-769662
Catalog No.: 3437

A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity.

Chemical Name: Thieno[2,3-b]pyridine-5-carbonitrile, 6,7-dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-

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Biological Activity:
A-769662 is a potent, reversible AMPK activator with EC50of 0.8 μM, little effect on GPPase/FBPase activity.
Technical Data:
M.W. 360.39
Formula:

C20H12N2O3S

Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 844499-71-4
References:
Cool B, et al, Cell Metab, 2006, 3(6), 403-416. Sanders MJ, J Biol Chem, 2007, 282(45), 32539-32548. Moreno D, et al, FEBS Lett, 2008, 583(17), 2650-2654. Pevton KJ, et al, J Pharmacol Exp Ther, 2012, Jun 13.

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Tags: Inhibitors, PI3K/Akt/mTOR, AMPK, A-769662, 844499-71-4

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